in PvE it doesn't really matter. In PvP however, most people would want you to bring a bow grip of fortitude.
I think you are viewing what the grip of fortitude does, a little different from what most people view it as. What is so good about the bow grip of fortitude, is the +30 HP. In PvP, there are builds known as "spike builds" that are designed to take out an entire player's HP in one quick strike, leaving no room for healing. More often times than not, the +30 HP is what will leave the player alive, barely, but still alive.
Bow grip of defense is better if you are constantly taking damage. I know when I run droknars forge, I prefer a sword handle of defense, because it reduces all damage by 1. 1 damage every hit may not seem like alot, however, you will probably take many more hits than just 30 in any small skirmish.
Honestly, its up to you. I know I like to PvP with my ranger as well, as I've got the ability and equipment to do so, so I pack fortitude grips on my bows, however I have a friend who does not PvP alot with her PvE cahracters, and therefore prefers the defense grip.
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